:root{--lightningcss-light:initial;--lightningcss-dark: ;color-scheme:light;color:#172126;--surface:#fbfdfd;--surface-2:#f4f8f8;--line:#cbd8d8;--line-strong:#9fb4b4;--ink:#172126;--muted:#5f7175;--teal:#0f8f8c;--teal-dark:#096461;--cyan:#dff7f6;--amber:#a96800;--amber-bg:#fff2d7;--red:#b42318;--red-bg:#ffe8e5;--green:#157347;--green-bg:#e7f7ee;--navy:#17324d;--shadow:0 12px 34px #17324d14;background:#eef3f3;font-family:Inter,ui-sans-serif,system-ui,-apple-system,BlinkMacSystemFont,Segoe UI,sans-serif}*{box-sizing:border-box}body{min-width:320px;margin:0}button,input,textarea,select{font:inherit}button{cursor:pointer}button:disabled{cursor:not-allowed;opacity:.62}.landing{background-color:#eef3f3;background-image:linear-gradient(#0f8f8c0e 1px,#0000 1px),linear-gradient(90deg,#0f8f8c0e 1px,#0000 1px),none;background-position:0 0,0 0,0 0;background-repeat:repeat,repeat,repeat;background-size:28px 28px;background-attachment:scroll,scroll,scroll;background-origin:padding-box,padding-box,padding-box;background-clip:border-box,border-box,border-box;place-items:center;min-height:100vh;padding:28px;display:grid}.home-stack{gap:14px;width:min(960px,100%);display:grid}.creator{background:var(--surface);border:1px solid var(--line);width:min(720px,100%);box-shadow:var(--shadow);justify-self:center;gap:16px;padding:24px;display:grid}.workspace-picker{justify-self:center;gap:10px;width:min(720px,100%);display:grid}.workspace-picker-list{gap:8px;display:grid}.workspace-picker-list button{white-space:normal;text-align:left;justify-content:flex-start}.creator-header,.topbar,.stage-header,.panel-title,.rail-title,.topbar-actions,.form-row,.stage-item-top,.label-row,.context-meter{align-items:center;display:flex}.creator-header,.topbar,.stage-header{justify-content:space-between;gap:18px}.eyebrow{color:var(--teal-dark);letter-spacing:0;text-transform:uppercase;margin:0 0 4px;font-size:12px;font-weight:800}h1,h2{letter-spacing:0;margin:0}h1{font-size:24px}h2{font-size:20px}label{color:#243840;gap:7px;font-size:13px;font-weight:750;display:grid}input,textarea,select{border:1px solid var(--line-strong);width:100%;color:var(--ink);background:#fff;outline:none;padding:10px 11px}textarea{resize:vertical;line-height:1.5}input:focus,textarea:focus,select:focus{border-color:var(--teal);box-shadow:0 0 0 3px #0f8f8c24}.disclaimer,.safety-strip,.warning-mini{background:var(--amber-bg);color:#6c4300;border:1px solid #f1bd90;padding:10px 12px;font-size:13px}.mode-grid{grid-template-columns:repeat(2,minmax(0,1fr));gap:10px;display:grid}.mode-card{border:1px solid var(--line);background:var(--surface-2);grid-template-columns:auto auto 1fr;align-items:center;gap:10px;padding:14px;display:grid}.mode-card input{width:auto}.mode-card span{gap:4px;min-width:0;display:grid}.mode-card strong{color:var(--navy);font-size:13px}.mode-card small{color:var(--muted);font-weight:650;line-height:1.35}.creator-workflow-fields{border:1px solid var(--line);background-color:#fbfdfd;background-image:linear-gradient(#0f8f8c0b 1px,#0000 1px),linear-gradient(90deg,#0f8f8c0b 1px,#0000 1px),none;background-position:0 0,0 0,0 0;background-repeat:repeat,repeat,repeat;background-size:18px 18px;background-attachment:scroll,scroll,scroll;background-origin:padding-box,padding-box,padding-box;background-clip:border-box,border-box,border-box;gap:12px;padding:14px;display:grid}.workflow-field-header{color:var(--navy);grid-template-columns:auto minmax(0,1fr);align-items:start;gap:9px;display:grid}.workflow-field-header svg{color:var(--teal-dark);margin-top:2px}.workflow-field-header div{gap:3px;display:grid}.workflow-field-header strong{font-size:13px}.workflow-field-header span{color:var(--muted);font-size:12px;font-weight:650;line-height:1.35}.drug-search-field{align-content:start;position:relative}.field-hint{color:var(--muted);font-size:11px;font-weight:650;line-height:1.35}.drug-result-list{border:1px solid var(--line-strong);max-height:240px;box-shadow:var(--shadow);z-index:3;background:#fff;display:grid;overflow:auto}.drug-result{border:0;border-bottom:1px solid var(--line);width:100%;min-height:0;color:var(--ink);text-align:left;background:#fff;grid-template-columns:minmax(0,1fr) auto;align-items:start;gap:10px;padding:10px;display:grid}.drug-result:hover,.drug-result.selected{background:var(--cyan)}.drug-result span{gap:3px;min-width:0;display:grid}.drug-result strong,.drug-result small{overflow-wrap:anywhere}.drug-result small{color:var(--muted);font-size:11px;font-weight:650}.drug-result code{color:var(--teal-dark);white-space:nowrap;font-size:11px}.primary,.secondary,.icon-button,.tutor-actions button{white-space:nowrap;border:1px solid #0000;justify-content:center;align-items:center;gap:8px;min-height:38px;padding:9px 13px;font-weight:800;display:inline-flex}.danger-action{color:var(--red)}.danger-action:hover{border-color:var(--red);color:var(--red)}.primary{background:var(--teal);color:#fff}.primary:hover{background:var(--teal-dark)}.secondary,.icon-button,.tutor-actions button{color:var(--navy);border-color:var(--line-strong);background:#fff}.secondary:hover,.icon-button:hover,.tutor-actions button:hover{border-color:var(--teal);color:var(--teal-dark)}.app-shell{grid-template-rows:auto auto 1fr auto;min-height:100vh;display:grid}.topbar{background:var(--surface);border-bottom:1px solid var(--line);padding:14px 18px}.topbar-actions{flex-wrap:wrap;justify-content:flex-end;gap:8px}.topbar select{min-width:220px}.safety-strip{border-left:0;border-right:0;justify-content:space-between;align-items:center;gap:12px;margin:0;display:flex}.safety-strip span{color:#17324d;font-family:ui-monospace,SFMono-Regular,Menlo,Monaco,Consolas,monospace}.workspace{grid-template-columns:294px minmax(0,1fr) 342px;min-height:0;display:grid}.workspace.left-collapsed{grid-template-columns:minmax(0,1fr) 342px}.workspace.right-collapsed{grid-template-columns:294px minmax(0,1fr)}.workspace.left-collapsed.right-collapsed{grid-template-columns:minmax(0,1fr)}.workspace-editor{border-bottom:1px solid var(--line);background:#f8fbfb;grid-template-columns:repeat(5,minmax(120px,1fr));gap:10px;padding:12px 18px;display:grid}.workspace-editor .editor-wide{grid-column:1/-1}.editor-actions{grid-column:1/-1;justify-content:flex-end;gap:8px;display:flex}.stage-rail,.tutor{border-right:1px solid var(--line);background:#f8fbfb;min-height:0;overflow:auto}.tutor{border-right:0;border-left:1px solid var(--line);padding:14px}.rail-title,.panel-title{color:var(--navy);justify-content:space-between;gap:8px;font-weight:850}.rail-title{border-bottom:1px solid var(--line);justify-content:flex-start;padding:14px}.stage-list{gap:8px;padding:10px;display:grid}.stage-item{text-align:left;border:1px solid var(--line);color:var(--ink);background:#fff;gap:8px;padding:12px;display:grid}.stage-item.active{border-color:var(--teal);box-shadow:inset 3px 0 0 var(--teal)}.stage-code,.badge,pre,code{font-family:ui-monospace,SFMono-Regular,Menlo,Monaco,Consolas,monospace}.stage-code{color:var(--teal-dark);font-weight:900}.stage-item strong{font-size:13px;line-height:1.35}.stage-metrics,.label-row,.provenance-stack{flex-wrap:wrap;gap:6px;display:flex}.badge{border:1px solid var(--line);color:#35474d;background:#f5f7f7;align-items:center;width:fit-content;padding:3px 7px;font-size:11px;font-weight:850;line-height:1.2;display:inline-flex}.badge-safe{background:var(--green-bg);color:var(--green);border-color:#b8e4c9}.badge-warn{background:var(--amber-bg);color:var(--amber);border-color:#f1d49a}.badge-danger{background:var(--red-bg);color:var(--red);border-color:#f3b1aa}.badge-info{background:var(--cyan);color:var(--teal-dark);border-color:#abdbda}.workbench{align-content:start;gap:14px;min-width:0;padding:16px;display:grid;overflow:auto}.stage-header,.visual-lab,.panel{background:var(--surface);border:1px solid var(--line);box-shadow:0 2px #17324d05}.stage-header{padding:16px}.stage-header p{color:var(--muted);margin:6px 0 0}.visual-lab{background-color:#f9fcfc;background-image:linear-gradient(#0f8f8c14 1px,#0000 1px),linear-gradient(90deg,#0f8f8c14 1px,#0000 1px),none;background-position:0 0,0 0,0 0;background-repeat:repeat,repeat,repeat;background-size:22px 22px;background-attachment:scroll,scroll,scroll;background-origin:padding-box,padding-box,padding-box;background-clip:border-box,border-box,border-box;min-height:170px;padding:16px}.lab-grid{grid-template-columns:minmax(0,1fr) 220px;align-items:center;gap:18px;min-height:138px;display:grid}.molecule-orbit{border:2px solid var(--teal);border-radius:50%;width:84px;height:84px;margin-bottom:12px;display:block;position:relative}.molecule-orbit:before,.molecule-orbit:after{content:"";background:var(--teal);border-radius:50%;position:absolute}.molecule-orbit:before{width:14px;height:14px;top:16px;left:12px;box-shadow:42px 22px #17324d,24px 50px #a96800}.molecule-orbit:after{border-radius:0;width:52px;height:2px;top:40px;left:16px;transform:rotate(25deg)}.visual-lab p{max-width:720px;color:var(--muted);line-height:1.5}.molecule-lab{min-height:0;padding:12px}.workflow-guide{gap:10px;padding:14px;display:grid}.workflow-guide .panel-title span{align-items:center;gap:7px;display:inline-flex}.workflow-guide p{color:var(--muted);margin:0;line-height:1.45}.workflow-checklist{grid-template-columns:repeat(3,minmax(0,1fr));gap:8px;display:grid}.workflow-check{border:1px solid var(--line);color:#243840;background:#f7fbfb;grid-template-columns:auto minmax(0,1fr);align-items:start;gap:7px;min-width:0;padding:10px;font-size:12px;font-weight:720;line-height:1.35;display:grid}.workflow-check svg{color:var(--teal-dark);margin-top:1px}.r1-workbench{gap:14px;display:grid}.r1-topline{justify-content:space-between;align-items:start;gap:16px;display:flex}.r1-topline .panel-title{justify-content:flex-start}.r1-topline .panel-title span{align-items:center;gap:7px;display:inline-flex}.r1-topline p{color:var(--muted);margin:8px 0 0;line-height:1.45}.r1-visual-grid{grid-template-columns:minmax(280px,.9fr) minmax(320px,1.1fr);gap:12px;display:grid}.r1-readiness-card,.r1-canvas{border:1px solid var(--line);background:#fbfdfdeb;padding:12px}.r1-readiness-card{grid-template-columns:116px minmax(0,1fr);align-items:center;gap:14px;display:grid}.metric-ring{aspect-ratio:1;background:radial-gradient(circle at center, #fff 0 58%, transparent 59%), conic-gradient(var(--teal) var(--score), #dce8e8 0);border:1px solid var(--line);border-radius:50%;place-items:center;width:108px;display:grid}.metric-ring strong,.metric-ring span{grid-area:1/1}.metric-ring strong{color:var(--navy);font-size:28px;line-height:1;transform:translateY(-7px)}.metric-ring span{color:var(--muted);text-transform:uppercase;font-size:10px;font-weight:800;transform:translateY(19px)}.readiness-lists{gap:10px;min-width:0;display:grid}.readiness-lists h3{color:var(--navy);text-transform:uppercase;margin:0 0 7px;font-size:12px}.readiness-lists>div{flex-wrap:wrap;gap:6px;display:flex}.r1-canvas{grid-template-columns:repeat(2,minmax(0,1fr));gap:10px;display:grid}.r1-canvas div{border:1px solid var(--line);background-color:#fff;background-image:linear-gradient(#0f8f8c0f 1px,#0000 1px),linear-gradient(90deg,#0f8f8c0f 1px,#0000 1px),none;background-position:0 0,0 0,0 0;background-repeat:repeat,repeat,repeat;background-size:18px 18px;background-attachment:scroll,scroll,scroll;background-origin:padding-box,padding-box,padding-box;background-clip:border-box,border-box,border-box;align-content:start;gap:7px;min-height:96px;padding:12px;display:grid}.r1-canvas svg{color:var(--teal-dark)}.r1-canvas span{color:var(--muted);text-transform:uppercase;font-size:12px;font-weight:850}.r1-canvas strong{color:var(--navy);font-size:18px}.brief-form-grid{grid-template-columns:repeat(2,minmax(0,1fr));gap:12px;display:grid}.brief-form-grid .wide-field{grid-column:1/-1}.brief-form-grid textarea{min-height:96px}.r1-report-preview{border:1px solid var(--line);background:#fbfdfdf0;gap:10px;padding:12px;display:grid}.r1-report-preview .panel-title span{align-items:center;gap:7px;display:inline-flex}.report-section-grid{grid-template-columns:repeat(3,minmax(0,1fr));gap:10px;display:grid}.report-section-grid div{border:1px solid var(--line);background:#fff;min-width:0;padding:11px}.report-section-grid h3{color:var(--navy);text-transform:uppercase;margin:0 0 8px;font-size:13px}.report-section-grid p{color:#35474d;margin:0 0 8px;font-size:13px;line-height:1.45}.molecule-lab-grid{grid-template-columns:1fr;align-items:start;gap:12px;display:grid}.molecule-controls,.molecule-card{border:1px solid var(--line);background:#fbfdfdeb;align-content:start;gap:10px;min-width:0;padding:12px;display:grid}.molecule-controls .panel-title span{align-items:center;gap:7px;display:inline-flex}.compound-search{grid-template-columns:minmax(190px,1fr) minmax(124px,auto);align-items:stretch;gap:8px;display:grid}.molecule-actions{flex-wrap:wrap;align-items:center;gap:8px;display:flex}.molecule-actions button{flex:160px;min-width:0}.pubchem-results{border:1px solid var(--line);background:#fff;max-height:142px;overflow:auto}.compound-result{border:0;border-bottom:1px solid var(--line);width:100%;color:var(--ink);text-align:left;background:#fff;justify-content:space-between;gap:8px;padding:8px 10px;display:flex}.compound-result:hover{background:var(--surface-2)}.compound-result span{text-overflow:ellipsis;min-width:0;overflow:hidden}.structure-frame{border:1px solid var(--line);background:#fff;place-items:center;height:clamp(260px,32vw,360px);min-height:260px;display:grid;overflow:hidden}.structure-frame svg{width:100%;height:100%;max-height:100%;display:block}.descriptor-grid{border:1px solid var(--line);background:#fff;grid-template-columns:repeat(4,minmax(0,1fr));display:grid}.descriptor-grid div{border-right:1px solid var(--line);border-bottom:1px solid var(--line);min-width:0;padding:8px}.descriptor-grid span{color:var(--muted);text-transform:uppercase;font-size:11px;font-weight:800;display:block}.descriptor-grid strong{color:var(--navy);overflow-wrap:anywhere;margin-top:4px;font-family:ui-monospace,SFMono-Regular,Menlo,Monaco,Consolas,monospace;font-size:13px;display:block}.panel{padding:14px}.notes-panel{gap:10px;display:grid}.evidence-grid{grid-template-columns:minmax(0,1.5fr) minmax(260px,.8fr);gap:14px;display:grid}.compact-form{gap:8px;margin:12px 0;display:grid}.form-row{gap:8px}.inline-edit-form{gap:8px;display:grid}.form-row .icon-button{flex:0 0 44px;width:44px;padding:0}.row-actions{flex-wrap:wrap;align-items:center;gap:6px;display:flex}.row-actions .icon-button{width:34px;min-height:34px;padding:0}.table-wrap{border:1px solid var(--line);overflow:auto}table{border-collapse:collapse;background:#fff;width:100%;font-size:13px}th,td{border-bottom:1px solid var(--line);text-align:left;vertical-align:top;padding:9px}th{color:var(--navy);background:var(--surface-2);font-size:12px}td{color:#25373d}.assumption-list{gap:8px;display:grid}.assumption{border:1px solid var(--line);background:#fff;gap:6px;padding:10px;display:grid}.assumption-header{justify-content:space-between;align-items:flex-start;gap:8px;display:flex}.assumption p,.muted{color:var(--muted);margin:0}.tutor{align-content:start;gap:12px;display:grid}.warning-mini{font-size:12px}.tutor-actions{gap:8px;display:grid}.tutor-actions button{justify-content:flex-start;width:100%}.context-meter{color:var(--muted);justify-content:space-between;font-size:12px}.context-meter strong{color:var(--navy);font-family:ui-monospace,SFMono-Regular,Menlo,Monaco,Consolas,monospace}.tutor-output{border:1px solid var(--line);background:#fff;min-height:220px;padding:12px}pre{white-space:pre-wrap;color:#25373d;margin:10px 0 0;font-size:12px;line-height:1.55}.report-preview{max-height:480px;overflow:auto}.empty-state{border:1px dashed var(--line-strong);text-align:center;color:var(--muted);padding:30px}.statusbar{border-top:1px solid var(--line);min-height:28px;color:var(--muted);background:#f8fbfb;padding:6px 12px;font-size:12px}@media (width<=1180px){.workspace,.workspace.left-collapsed,.workspace.right-collapsed{grid-template-columns:250px minmax(0,1fr)}.workspace.left-collapsed{grid-template-columns:minmax(0,1fr)}.workspace.left-collapsed .tutor,.tutor{border-left:0;border-top:1px solid var(--line);grid-column:1/-1}.workspace.right-collapsed{grid-template-columns:250px minmax(0,1fr)}.workspace.left-collapsed.right-collapsed{grid-template-columns:minmax(0,1fr)}}@media (width<=820px){body{overflow-x:hidden}.topbar,.stage-header,.creator-header{flex-direction:column;align-items:flex-start}.topbar select,.topbar-actions,.topbar-actions button{width:100%;min-width:0}.workspace,.workspace.left-collapsed,.workspace.right-collapsed,.workspace.left-collapsed.right-collapsed,.evidence-grid,.lab-grid,.r1-visual-grid,.brief-form-grid,.report-section-grid,.molecule-lab-grid,.mode-grid,.workflow-checklist{grid-template-columns:1fr}.workspace-editor{grid-template-columns:1fr;padding:12px 10px}.editor-actions{justify-content:stretch}.editor-actions button{flex:1}.workbench{width:100%;max-width:100vw;padding:12px 10px;overflow-x:hidden}.r1-workbench,.r1-readiness-card,.r1-canvas,.brief-form-grid,.brief-form-grid label,.brief-form-grid textarea{width:100%;min-width:0}.r1-workbench{max-width:calc(100vw - 20px);overflow:hidden}.r1-topline p,.r1-canvas strong,.readiness-lists,.readiness-lists>div,.badge{overflow-wrap:anywhere;white-space:normal;max-width:100%}.r1-canvas,.r1-topline,.r1-readiness-card{grid-template-columns:1fr}.r1-topline{flex-direction:column}.descriptor-grid{grid-template-columns:1fr 1fr}.compound-search{grid-template-columns:1fr}.molecule-actions button{flex-basis:100%}.stage-rail{border-right:0;border-bottom:1px solid var(--line);max-height:360px}.topbar-actions{justify-content:flex-start;width:100%}.topbar select{min-width:0}.safety-strip{flex-direction:column;align-items:flex-start}}